Pattern of distribution of patients presenting with osteogenesis imperfecta at A.I.C. Cure Children’s International Hospital, Kijabe

Abstract

Objective:

The study was carried out to determine the tribal and geographical distribution of patients with osteogenesis imperfecta in Kenya.

Design:

This was a 14 year retrospective review study.

Setting:

Cure Hospital, Kenya.

Materials and Methods:

The medical charts of all patients admitted with  Osteogenesis Imperfecta (OI) over a period of 14 years [2000 to 2014] were reviewed.

Results:

A total of 80 patients with osteogenesis imperfecta were seen. Fifty seven point five percent of the patients with OI were males and 42.5% were females. Thirty seven point five percent were of Kamba origin while 28.8% were from the Kikuyu tribe. Majority of these patients came from Eastern region of Kenya with 26.25% coming from Machakos and 30 out of the total of 80 patients were from Kamba tribe.

Conclusions:

Most of these patients come from Eastern region of Kenya. Majority of patients with OI were of Kamba origin followed by the Kikuyu tribe. A larger epidemiological study needs to be carried out to more conclusively determine the relative prevalence and genetic patterns of osteogenesis imperfecta in Kenya.