Research Pattern of Distribution of Patients Presenting with Osteogenesis Imperfecta at A.I.C. Cure Children’s International Hospital, Kijabe

Pattern of Distribution of Patients Presenting with Osteogenesis Imperfecta at A.I.C. Cure Children’s International Hospital, Kijabe

Pattern of Distribution of Patients Presenting with Osteogenesis Imperfecta at A.I.C. Cure Children’s International Hospital, Kijabe

Abstract

Objective

The study was carried out to determine the tribal and geographical distribution of patients with osteogenesis imperfecta in Kenya.

Design

This was a 14 year retrospective review study.

Setting

Cure Hospital, Kenya.

Materials and Methods

The medical charts of all patients admitted with  Osteogenesis Imperfecta (OI) over a period of 14 years [2000 to 2014] were reviewed.

Results

A total of 80 patients with osteogenesis imperfecta were seen. Fifty seven point five percent of the patients with OI were males and 42.5% were females. Thirty seven point five percent were of Kamba origin while 28.8% were from the Kikuyu tribe. Majority of these patients came from Eastern region of Kenya with 26.25% coming from Machakos and 30 out of the total of 80 patients were from Kamba tribe.

Conclusions

Most of these patients come from Eastern region of Kenya. Majority of patients with OI were of Kamba origin followed by the Kikuyu tribe. A larger epidemiological study needs to be carried out to more conclusively determine the relative prevalence and genetic patterns of osteogenesis imperfecta in Kenya.